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Tramadol APAP, Generic Ultracet (Tramadol with Acetaminophen):

Generic Ultracet 37.5/325 mg, 30 tablets
Generic Ultracet 37.5/325 mg, 60 tablets
Generic Ultracet 37.5/325 mg, 90 tablets

TRAMADOL DRUG INFORMATION

TRAMADOL - ORAL (TRAH-muh-dall)

COMMON BRAND NAMES: Ultram®

WHAT IS TRAMADOL

Tramadol is used to relieve pain.

HOW TO USE TRAMADOL

Take Tramadol by mouth as exactly as prescribed. A typical dose is every 4 to 6 hours as needed. Do not take more or use it more often or use it for a longer period of time than prescribed because Tramadol can be habit-forming.

If you use it for an extended period of time, do not suddenly stop using Tramadol without your doctor's approval.

When used an extended period of time, Tramadol may not work as well and may require different dosing. Talk to your doctor if the medication stops working well.

TRAMADOL SIDE EFFECTS

If any of these Tramadol side effects persist or worsen, inform your doctor

• anxiety
• constipation
• dizziness
• drowsiness
• dry mouth
• increased sweating
• headache
• irritability
• lack of coordination
• nausea or vomiting
• stomach upset
• weakness

If you develop any of these serious Tramadol side affects, notify your doctor

• chest pain
• disorientation
• mental confusion
• rapid heart rate
• seizures
• skin rash or itching
• tingling of the hands or feet
• trouble breathing

TRAMADOL ALLERGIC REACTION

It is unlikely that you will have an allergic reaction from Tramadol, however it could occur. If you experience any of these symptoms, call your doctor

• breathing trouble
• dizziness
• itching
• rash
• swelling

TRAMADOL PRECAUTIONS

Before you take Tramadol tell your doctor your medical history, especially

• any allergies
• history of drug or alcohol dependency
• kidney disease
• liver disease
• lung disease
• seizure disorder

Alcohol may add to the dizziness or drowsiness effects caused Tramadol. It is best to limit your consumption.

Because Tramadol may make you dizzy or drowsy, use caution performing tasks requiring alertness such as driving.

TRAMADOL and PREGNANCY

Tramadol should be used only when clearly needed during pregnancy. Discuss the benefits and risks with your doctor.

TRAMADOL and BREAST FEEDING

Tramadol is excreted into breast milk. Since the effects on a nursing infant are not known, consult your doctor before breast- feeding.

TRAMADOL DRUG INTERACTIONS

Tell your doctor about all prescription and over-the-counter medications you use, especially:

• anti-anxiety drugs (e.g., diazepam)
• anti-depressants (e.g., SSRI-types such as fluvoxamine or fluoxetine)
• carbamazepine
• MAO inhibitors (e.g., furazolidone, linezolid, procarbazine, phenelzine, selegiline, tranylcypromine)
• narcotic pain relievers (e.g., codeine)
• psychiatric medicine (e.g., nefazodone)
• sibutramine
• sleep aids
• "triptan"-type drugs

Also, tell your doctor if you use certain antihistamines (e.g., diphenhydramine) which are also present in many over-the-counter cough-and-cold products.

Do not start or stop any medicine without your doctor's.

OVERDOSE

If a Tramadol overdose is suspected, contact your local poison control center (1-800-222-1222) or emergency room (911) immediately.

Symptoms of overdose may include

• deep sleep
• drowsiness
• dizziness
• lightheadedness
• loss of consciousness
• seizures
• slowed breathing
• cold and clammy skin
• low body temperature
• slowed heartbeat

NOTES

Do not share Tramadol with others.

MISSED DOSE

If you miss a dose, take it as soon as you remember. However, if it is near the time for the next dose, do not take the missed dose. Rather, skip the missed dose and resume your usual dosing schedule. Do not take a double dose to catch up.

STORAGE

Store Tramadol at room temperature between 59 and 86 degrees F (15 to 30 degrees C) away from heat and light. Avoid excessive moisture. Do not store in the bathroom. Keep out of the reach of children.

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